CBD and THC are the two most well-known cannabinoids in the hemp and cannabis world. You'll find them in tinctures, gummies, topicals, vapes, and flower — sometimes together, sometimes separately. Both come from the Cannabis sativa plant. Both interact with the body's endocannabinoid system. But they work in very different ways and produce very different effects.

If you've been wondering which one is right for your needs, this guide will help you understand the key differences.

What Is CBD?

CBD (cannabidiol) is a non-intoxicating cannabinoid found in high concentrations in hemp plants. "Non-intoxicating" means CBD will not get you high — it does not produce the euphoric or altered-state effects associated with THC.

CBD is legal at the federal level when derived from hemp with ≤ 0.3% Delta-9 THC. It's widely used for its potential to support relaxation, stress management, sleep, and physical comfort. CBD interacts with the endocannabinoid system indirectly — rather than binding tightly to CB1 receptors (which cause intoxication), it works through other pathways.

What Is THC?

THC (tetrahydrocannabinol) — specifically Delta-9 THC — is the primary psychoactive compound in cannabis. It binds directly to CB1 receptors in the brain, which is what causes the classic cannabis "high": euphoria, relaxation, altered perception of time, and increased appetite.

Hemp-derived Delta-9 THC is legal under the 2018 Farm Bill as long as the product contains ≤ 0.3% Delta-9 THC by dry weight. Other THC variants sold in hemp stores include Delta-8 THC, Delta-10 THC, THCA, and THCP — each with slightly different effects and legal statuses.

CBD vs. THC: Key Differences at a Glance

Can You Take CBD and THC Together?

Yes — and many people do. This is called the "entourage effect": a theory suggesting that cannabinoids, terpenes, and other compounds in hemp work better together than in isolation. Full-spectrum hemp products contain both CBD and trace amounts of THC (≤ 0.3%), along with minor cannabinoids like CBG, CBN, and CBC.

Many users report that full-spectrum products feel more effective than CBD isolate alone. If you're sensitive to THC or subject to drug testing, broad-spectrum products (THC removed) or CBD isolate may be a better fit.

Which One Should You Choose?

• Choose CBD if you want relaxation, sleep support, or daily wellness without any intoxicating effect.
• Choose hemp-derived Delta-9 THC if you want mild euphoria and relaxation and are comfortable with a light psychoactive experience.
• Choose full-spectrum CBD (contains trace THC) if you want the combined benefits of all cannabinoids with minimal intoxication.
• Avoid THC products if you're subject to workplace drug testing — even compliant hemp-derived THC can accumulate in the body and trigger a positive test.

Browse CBDsStore.com's full selection of CBD and THC hemp products — all third-party lab tested and shipped free to all 50 states.

⚠️ These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Must be 21+ to purchase.